Microsoft Corporation Informative - Wireless Laser Mouse 6000 V2
The version that I own is designed for right handed folks. I have yet to experience any issues with the device. The receiver for this mouse plugs into any USB port. The receiver looks just like a USB drive. Beats the older style that sat on the desktop with a cord that was hooked to the computer.
The wheel and every button on the mouse is configurable. I've left everything but the two thumb buttons with their default settings.
If you're in the market for a wireless mouse, you might want to consider this model. Try it out first at the local electronics or office store. The key consideration for a mouse is how it feels in your hand.